Supported DNA Files: What Data Can I Use With Mutant?

Mutant can analyze compatible genetic data you already have from:

You do not need to purchase a new DNA test if you already have supported genetic data.

And your complete raw DNA file does not need to be uploaded to Mutant.

When you select your DNA data, Mutant reads it locally in your browser, identifies the genetic markers needed for the analysis, and sends only those required markers.

Add Your DNA Data → Compare Consumer DNA vs Whole-Genome Sequencing →
Your complete raw DNA stays in your browser.

Quick Answer

Mutant is designed to work with raw genetic data, not screenshots or summary reports.

Supported DNA Sources

DNA source Supported What to expect
23andMe raw data Yes Useful coverage across many Mutant models; some markers may be missing
AncestryDNA raw data Yes Useful coverage across many Mutant models; some markers may be missing
Selected WGS formats Yes Generally broader coverage and fewer missing markers
PDF health reports No Reports do not contain the structured genetic data Mutant needs
Screenshots No Images cannot provide the required genotype dataset
Trait summaries No Summary results are not equivalent to raw genetic data

Your DNA source affects coverage, not the type of Mutant analysis you receive.


What Is a Raw DNA File?

A raw DNA file is the underlying genetic-data export provided by a DNA testing or sequencing service.

Depending on the source, it may contain information such as:

A simplified consumer-DNA record might look like:

rs123456    1    12345678    AG

This is very different from a health or ancestry report.

A report gives you an interpretation.

Raw genetic data provides the underlying information Mutant needs to perform its own analysis.


23andMe Raw DNA Data

Mutant supports compatible 23andMe raw DNA data.

If you previously tested with 23andMe, you may already have the genetic data needed to start a Mutant analysis.

You generally want the provider's raw genetic data export, not:

Mutant can use available 23andMe markers across biological areas such as:

Coverage depends on your 23andMe testing version.

Some genetic markers used by Mutant may not be present.


AncestryDNA Raw DNA Data

Mutant also supports compatible AncestryDNA raw genetic data.

As with 23andMe, you need the provider's raw DNA export rather than an ancestry or trait summary.

AncestryDNA can provide useful markers across many Mutant biological models.

However, the exact markers available depend on:

Some Mutant markers may therefore be missing.

That does not make the file unusable.

Mutant analyzes the genetic evidence that is actually available.


Whole-Genome Sequencing

Mutant also supports selected whole-genome sequencing formats.

Whole-genome sequencing differs from consumer genotyping because it reads much more broadly across the genome rather than checking only a predefined collection of locations.

For Mutant, the main advantage is:

More of the genetic markers used by Mutant's models are generally available.

This can mean:

WGS does not provide a different Mutant product.

It provides broader genetic coverage for the same Mutant analysis framework.


Your DNA Source Affects Coverage, Not the Analysis

Mutant does not have a basic consumer-DNA analysis and a separate advanced WGS analysis.

All supported DNA sources use the same framework:

Genetic markers
↓
Genetic module patterns
↓
Converging patterns
↓
Ranked health hypotheses
↓
Supporting evidence + coverage
↓
Health Context

What changes is how much relevant genetic information is available.

23andMe or AncestryDNA

Same Mutant analysis
+ useful genetic evidence
+ more potential gaps

Whole-genome sequencing

Same Mutant analysis
+ broader genetic evidence
+ generally fewer gaps

Missing Markers Are Treated as Missing Data

Consumer DNA services do not test every genetic location Mutant may use.

If a marker is absent from your DNA source, Mutant should not assume that you have:

The result is simply:

Missing genetic data

This distinction matters because a health hypothesis may have excellent coverage from one DNA source and limited coverage from another.


What Does “Relevant Variant Coverage” Mean?

Mutant can track how much of the genetic evidence required by its models was available from your DNA source.

For example, if a particular genetic model uses ten relevant markers and your DNA source contains eight of them, the remaining two are missing.

Coverage helps you understand how complete the available genetic evidence is.

It does not mean:

Mutant analyzed this percentage of your entire genome.

Instead, it means:

This percentage of the genetic markers Mutant wanted for this analysis was available.

Better Coverage Can Strengthen or Weaken a Hypothesis

More genetic data does not automatically mean more findings.

Suppose consumer DNA provides partial evidence for a health hypothesis.

Broader WGS data could reveal:

More supporting evidence

The hypothesis becomes more strongly supported.

Contradictory or compensating evidence

The hypothesis becomes less compelling.

Little additional evidence

The interpretation changes very little.

Evidence for another hypothesis

The ranking may change.

The purpose of broader DNA coverage is therefore not to produce a more dramatic analysis.

It is to reduce uncertainty.


What Files Should I Use?

Use the original genetic-data export whenever possible.

Your file should ideally:

Avoid manually modifying:

Changing the original genetic data can prevent accurate processing.


What Mutant Does Not Need

Mutant does not need:

These may contain useful information for other purposes, but they are not substitutes for the supported genetic-data source Mutant needs to run its models.


Your Complete Raw DNA Stays in Your Browser

Mutant is designed to minimize how much genetic information leaves your device.

When you add supported DNA data:

  1. You select the DNA data on your device.
  2. Your browser reads it locally.
  3. Mutant identifies the markers required for its current models.
  4. Only those required genetic markers are sent and retained.
  5. Your complete raw DNA remains on your device.
Your complete raw DNA is not uploaded or stored by Mutant.

This is especially important for WGS, where the complete source data can contain far more genetic information than Mutant needs.


Why Mutant Does Not Need Your Entire Genome

Mutant does not attempt to interpret every possible genetic variant.

It uses a defined collection of markers incorporated into its current biological models.

That means a WGS file may contain millions of genetic observations while Mutant needs only a subset of them.

Local browser processing allows Mutant to extract the relevant markers without retaining the entire genome.


Does Mutant Analyze Every Variant in WGS?

No.

Whole-genome sequencing provides broad source data.

Mutant evaluates the subset of genetic evidence used by its current models.

WGS support should therefore not be interpreted as:

Mutant provides a defined educational genetic analysis.


Consumer DNA vs WGS for Inherited-Health Findings

Coverage can become especially important for selected inherited-health patterns.

Mutant may evaluate genetic context involving areas such as:

Consumer DNA may contain some relevant variants while missing others.

WGS generally provides broader coverage.

However, even a potentially significant finding identified from WGS should not automatically be treated as a clinical diagnosis.

Depending on the finding, appropriate confirmation may include:

Mutant is not a substitute for diagnostic genetic testing.


Can I Start With 23andMe or AncestryDNA and Use WGS Later?

Yes.

You do not need to decide on WGS before using Mutant.

A practical sequence is:

  1. Start with compatible genetic data you already have.
  2. Review the resulting DNA coverage.
  3. Explore the hypotheses supported by your available genetics.
  4. Identify where important evidence is missing.
  5. Decide later whether broader sequencing is worth pursuing.

If you later obtain supported WGS data, you can use the broader genetic source to regenerate your analysis.

The Mutant framework remains the same.

The available genetic evidence changes.


Do I Need a New DNA Test?

Not necessarily.

If you already have compatible:

you can start with what you already have.

There is no reason to purchase another DNA test before seeing what coverage your current data provides.


Add Your DNA Data

When you are ready:

  1. Sign in to Mutant.
  2. Choose Add DNA Data.
  3. Select your DNA source.
  4. Choose the supported genetic-data file on your device.
  5. Mutant reads the file locally in your browser.
  6. Only the markers required for your analysis are sent and retained.
  7. Mutant generates your biological-system analysis and ranked health hypotheses.

You do not need to manually identify SNPs or convert the file yourself.


What Mutant Generates From Supported DNA

Mutant organizes available genetic evidence into several layers.

Biological Systems & Hubs

Genetics is grouped into related biological areas.

Current systems include:

Gut, Barrier & Immune Reactivity

Clinical & Inherited Health

Metabolic Reactivity

Stress, Mood & Neurochemical Regulation

Genetic Module Patterns

Related variants are organized into biological modules.

Converging Patterns

Mutant evaluates whether multiple independent genetic patterns point toward the same biological hypothesis.

Ranked Health Hypotheses

The available evidence is integrated into prioritized hypotheses describing genetic susceptibility.

These are health hypotheses, not diagnoses.

Supporting Evidence

You can inspect:

Health Context

Mutant can also identify the types of real-world information that may:

Health Context may include:


Mutant Free — $0

You can begin without purchasing Mutant Full.

Mutant Free includes:

Your top 3 hypotheses may come from any biological system or hub.

Start Your Free Analysis →

No credit card required.


Mutant Full — $49/year

Mutant Full unlocks all remaining findings available from your analysis.

Included:

Your subscription does not depend on whether your DNA comes from consumer genotyping or WGS.

Unlock Full Analysis →

DNA Source and Mutant Access Are Separate

There are two different concepts:

DNA Source

Determines:

What genetic evidence is available

Examples:

Mutant Access

Determines:

How much of the resulting analysis you can open

Mutant Free

Top 3 ranked health hypotheses are fully unlocked.

Mutant Full

All ranked health hypotheses are fully unlocked.

You can therefore use:

The underlying analysis framework remains the same.


Frequently Asked Questions

What DNA files does Mutant support?

Mutant currently supports compatible genetic data from:

  • 23andMe
  • AncestryDNA
  • Selected whole-genome sequencing formats

Support depends on the source and file structure.

Can I use my 23andMe raw DNA?

Yes.

Compatible 23andMe raw genetic data can be used with Mutant.

Coverage varies by testing version.

Learn About 23andMe Raw Data Analysis →

Can I use AncestryDNA?

Yes.

Compatible AncestryDNA raw genetic data can be used with Mutant.

Some markers required by Mutant's models may be missing.

Learn About AncestryDNA Raw Data Analysis →

Can I use whole-genome sequencing?

Yes, with selected supported WGS formats.

WGS generally provides broader coverage of the genetic markers used by Mutant.

Is WGS required?

No.

You can start with compatible 23andMe or AncestryDNA data you already have.

Is WGS a different Mutant analysis?

No.

All supported sources use the same Mutant analysis framework.

WGS generally provides broader genetic coverage.

Compare Consumer DNA vs Whole-Genome Sequencing →

Does Mutant analyze every variant in my WGS data?

No.

Mutant evaluates the subset of markers required by its current models.

Does Mutant upload my complete raw DNA?

No.

Your complete genetic data is read locally in your browser.

Only the genetic markers required for your Mutant analysis are sent and retained.

Can I use a PDF DNA report?

No.

A PDF report does not contain the complete structured raw genetic data Mutant requires.

Can I use screenshots?

No.

Mutant needs supported genetic data rather than images of genetic results.

Can I copy and paste my SNPs into Mutant?

Not as a replacement for supported DNA data.

Mutant is designed to process compatible genetic-data sources and determine which required markers are available.

Should I unzip my DNA file?

Follow the instructions shown by Mutant for your specific DNA source.

Avoid changing the contents of the provider's original genetic-data export unless instructed.

Should I edit the DNA file first?

No.

Use the original provider export whenever possible.

Manual edits can alter the structure or genetic information Mutant expects.

What if some variants are missing?

Mutant treats unavailable variants as missing data.

It does not assume they are normal, protective, or wild type.

Will a missing marker prevent my entire analysis?

Not necessarily.

Different hypotheses use different genetic evidence.

Your DNA may provide strong coverage for some models and limited coverage for others.

What does DNA coverage mean?

Coverage describes how much of the genetic evidence required by Mutant's models was available from your DNA source.

It does not describe what percentage of your complete genome Mutant interpreted.

Can I replace my DNA source later?

Yes.

If you later obtain another supported DNA source, such as WGS, you can use the broader data to regenerate your analysis.

Will changing from consumer DNA to WGS change my results?

It may.

Additional genetic evidence can:

  • Strengthen a hypothesis
  • Weaken a hypothesis
  • Change its ranking
  • Reveal additional patterns
  • Reduce uncertainty

The underlying Mutant analysis framework remains the same.

Does WGS guarantee complete coverage?

No.

WGS generally provides much broader coverage than consumer genotyping, but technical gaps can still exist.

Mutant also interprets only the genetic markers incorporated into its current models.

Does Mutant provide clinical genetic testing?

No.

Mutant provides educational and informational genetic analysis.

Potentially significant inherited findings may require appropriate clinical confirmation.

Is the health questionnaire required?

No.

The questionnaire is optional.

It can add Health Context, but it is not required to generate your genetic analysis.

Do different DNA sources cost different amounts?

No different Mutant plan is required because of your DNA source.

Mutant Free and Mutant Full determine access to your ranked health hypotheses, not whether your data came from 23andMe, AncestryDNA, or supported WGS.

What does Mutant Free include?

Mutant Free includes your top 3 ranked health hypotheses in full, including their evidence, contributing patterns, Health Context, coverage, and limitations.

What does Mutant Full include?

Mutant Full is $49/year and unlocks all ranked health hypotheses available from your analysis.


Start With the DNA You Already Have

You do not need the largest DNA file to begin.

If you already have compatible 23andMe or AncestryDNA data, use it.

Mutant will determine:

If broader WGS data becomes useful later, you can use it to reduce coverage gaps.

The important distinction is:

Your DNA source determines coverage.
Mutant determines how the available genetic evidence fits together.

Your top 3 ranked health hypotheses are included in full with Mutant Free.

Add Your DNA Data → Start Your Free Analysis → Compare Consumer DNA vs Whole-Genome Sequencing →

No credit card required.

Your complete raw DNA stays in your browser.

Related Pages


Mutant provides educational and informational genetic analysis. Its findings are health hypotheses, not diagnoses, and are not a substitute for medical evaluation, clinical genetic testing, or treatment.